Effects of exosomal circular RNA-100338 derived from hepatocellular carcinoma on angiogenesis of human umbilical vein endothelial cells

Objective To observe the effects of exosomal circular RNA (circRNA)-100338 derived from hepatocellular carcinoma (HCC) on angiogenesis of human umbilical vein endothelial cells (HUVEC). Methods The exosomes from the supernatant of MHCC97H cells were extracted, purified and identified, and co-incubated with HUVECs (37 ℃, 5% CO2). The exosome tracer experiments traced whether the exosomes could be transformed into HUVECs. MHCC97H cells were...