Radiobiologically derived biphasic fractionation schemes to overcome the effects of tumour hypoxia
Volume: 93, Issue: 1112, Pages: 20190250 - 20190250
Published: Aug 1, 2020
Abstract
As a fractionated course of radiotherapy proceeds tumour shrinkage leads to resolution of hypoxia and the initiation of accelerated proliferation of radioresistant cancer cells with better repair capacity. We hypothesise that, in tumours with significant hypoxia, improved tumour control could be achieved with biphasic fractionation schedules that either use acceleration after 3-4 weeks of conventional radiotherapy or deliver a higher...
Paper Details
Title
Radiobiologically derived biphasic fractionation schemes to overcome the effects of tumour hypoxia
Published Date
Aug 1, 2020
Journal
Volume
93
Issue
1112
Pages
20190250 - 20190250
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