A simple approach to room-temperature synthesis of cubic Al-doped HfO2 nanoparticles and their toxicity evaluation in normal prostate cells

Al-doped HfO2 nanoparticles were prepared at room-temperature using a novel one-step, straightforward, high-yield, efficient and green process. It includes a mechanically activated metathesis reaction that promotes the direct crystallization of cubic HfO2 (c-HfO2) in milling. Al-cation was used as dopant, achieving c-HfO2 stabilization at low content (5% mol). The c-HfO2 is stable up to 380 °C without exhibiting transformation from the cubic to...