Lactobacillus rhamnosus2016SWU.05.0601 regulates immune balance in ovalbumin‐sensitized mice by modulating expression of the immune‐related transcription factors and gut microbiota

BACKGROUND Probiotics regulate host immune balance, which may reduce immune‐related diseases. The effects and mechanisms of Lactobacillus rhamnosus 2016SWU.05.0601 (Lr‐0601) on the immune response in ovalbumin (OVA)‐sensitized mice were explored. RESULTS Lr‐0601 reduced serum immunoglobulin (Ig)E and OVA‐IgE and attenuated the alteration in lung pathology in OVA‐sensitized mice. Lr‐0601 blocked OVA‐induced up‐regulation in serum T helper (Th) 2...