Cytotoxicity of Platinum and Palladium Chelates against Osteosarcoma
Abstract
This work reports the half maximal inhibitory concentrations, IC 50 , for conventional anti‐cancer drug oxaliplatin (OXA) and potential new drugs Pt 2 Cl 2 Spm (Pt 2 Spm) and Pd 2 Cl 2 Spm (Pd 2 Spm) (Spm=Spermine) against osteosarcoma (OS). IC 50 values provided by the (3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) and Alamar Blue (AB) viability assays and cell density Sulforhodamine B (SRB) test were compared. Values...
Paper Details
Title
Cytotoxicity of Platinum and Palladium Chelates against Osteosarcoma
Published Date
May 27, 2020
Journal
Volume
5
Issue
20
Pages
5993 - 6000
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