Osteogenesis of dextran sulfate/recombinant human bone morphogenetic protein-2/chitosan nano microspheres combined with coralline hydroxyapatite in repair of large segmental bone defects

Volume: 19, Issue: 12, Pages: 1074 - 1080
Published: Dec 15, 2017
Abstract
Objective To investigate the osteogenic ability of dextran sulfate/recombinant human bone morphogenetic protein-2/chitosan (DS/rhBMP2/CS) nano microspheres combined with coralline hydroxyapatite (CHA) in repair of segmental bone defects. Methods DS/rhBMP2/CS microspheres prepared by ionic crosslinking method were adsorbed into CHA by lyophilization. Seventy-two New Zealand rabbits were randomly divided into 3 equal groups after they had...
Paper Details
Title
Osteogenesis of dextran sulfate/recombinant human bone morphogenetic protein-2/chitosan nano microspheres combined with coralline hydroxyapatite in repair of large segmental bone defects
Published Date
Dec 15, 2017
Volume
19
Issue
12
Pages
1074 - 1080
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