Polygenic risk scores: from research tools to clinical instruments
Abstract
Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of an individual’s susceptibility to diseases. Polygenic risk scores have been widely applied in research studies, confirming the association between the scores...
Paper Details
Title
Polygenic risk scores: from research tools to clinical instruments
Published Date
May 18, 2020
Journal
Volume
12
Issue
1
Pages
1 - 11
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