LPS-induced expression and release of monocyte tissue factor in patients with haemophilia
Abstract
In haemophilia, thrombin generation and fibrin deposition upon vascular injury critically depend on the tissue factor (TF)-driven coagulation pathway. TF expression by monocytes/macrophages and circulating microvesicles contributes to haemostasis, thrombosis and inflammation. Inflammation is a hallmark of blood-induced joint disease. The aim of this study is to correlate TF production by whole-blood monocytes with inflammatory markers and...
Paper Details
Title
LPS-induced expression and release of monocyte tissue factor in patients with haemophilia
Published Date
May 19, 2020
Journal
Volume
99
Issue
7
Pages
1531 - 1542
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