Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis
Abstract
Pain evoked by visceral inflammation is often ‘referred’ to the somatic level. Transient receptor potential ankyrin 1 (TRPA1) has been reported to contribute to visceral pain-like behavior in dextran sulfate sodium (DSS)-evoked colitis. However, the role of TRPA1 in somatic component of hypersensitivity due to visceral inflammation is unknown. The present study investigated the role of TRPA1 in colitis-evoked mechanical hypersensitivity at the...
Paper Details
Title
Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis
Published Date
May 25, 2020
Journal
Volume
10
Issue
1
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