Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV
Abstract
Chronic HIV-infected children suffer from premature aging and aging-related diseases. Viral replication induces an ongoing inflammation process, with the release of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), the activation of the immune system, and the production of proinflammatory cytokines. Although combined highly active antiretroviral therapy (ART) has significantly modified the natural...
Paper Details
Title
Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV
Published Date
May 16, 2020
Volume
2020
Pages
1 - 15
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