Autophagy-dependent mitochondrial function regulates osteoclast differentiation and maturation

Volume: 527, Issue: 4, Pages: 874 - 880
Published: Jul 1, 2020
Abstract
Bone homeostasis is maintained by bone remodeling, which involves continuous bone resorption by osteoclasts and bone formation by osteoblasts. Dysregulation of bone turnover, caused by osteoclast overactivation, causes destructive bone diseases. However, the mechanisms underlying the maintenance of osteoclast differentiation and activation are unclear. Herein, we examined the role of autophagy in the maintenance of osteoclast differentiation and...
Paper Details
Title
Autophagy-dependent mitochondrial function regulates osteoclast differentiation and maturation
Published Date
Jul 1, 2020
Volume
527
Issue
4
Pages
874 - 880
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