Substrate Resistance to Traction Forces Controls Fibroblast Polarization

Published: May 15, 2020
Abstract
null The mechanics of fibronectin-rich extracellular matrix regulate cell physiology in a number of diseases, prompting efforts to elucidate cell mechanosensing mechanisms at the molecular and cellular scale. Here, the use of fibronectin-functionalized silicone elastomers that exhibit considerable frequency-dependence in viscoelastic properties unveiled the presence of two cellular processes that respond discreetly to substrate mechanical...
Paper Details
Title
Substrate Resistance to Traction Forces Controls Fibroblast Polarization
Published Date
May 15, 2020
Journal
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