Abstract 166: Human Nrf2-Active Multipotent Stromal Cell Exosomes Reverse Pathologic Diabetic Wound Healing

Purpose: Multipotent stromal cells (MSCs) have attracted much attention for their capacity to accelerate wound healing. However, there are no approved MSC based therapies. Exosomes, nanosized extracellular vesicles, may be key to translating MSC therapy to the bedside. We previously found that nuclear-factor-erythroid-2-related -factor-2 (Nrf2) regulates MSC multipotency and promotion of diabetic tissue repair. Here, we explore a novel role of...