Slow versus fast rewarming after hypothermic circulatory arrest: effects on neuroinflammation and cerebral oedema

OBJECTIVES Among the factors that could determine neurological outcome after hypothermic circulatory arrest (HCA) rewarming is rarely considered. The optimal rewarming rate is still unknown. The goal of this study was to investigate the effects of 2 different protocols for rewarming after HCA on neurological outcome in an experimental animal model. METHODS Forty-four Sprague Dawley rats were cooled to 19 ± 1°C body core temperature by...