Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Abstract
Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype1-3. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls, plus 18,908 BRCA1 mutation carriers (9,414 with breast cancer) of European ancestry, using both standard and novel methodologies that account for underlying tumor heterogeneity by estrogen receptor, progesterone...
Paper Details
Title
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Published Date
May 18, 2020
Journal
Volume
52
Issue
6
Pages
572 - 581
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