A human monoclonal antibody blocking SARS-CoV-2 infection

Chunyan Wang; Wentao Li; Dubravka Drabek; Nisreen M.A. Okba; Rien van Haperen; Albert D.M.E. Osterhaus; Frank J. M. van Kuppeveld; Bart L. Haagmans; Frank Grosveld; Berend Jan Bosch

doi:https://doi.org/10.1038/s41467-020-16256-y

doi.org/10.1038/s41467-020-16256-y

A human monoclonal antibody blocking SARS-CoV-2 infection

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..., Berend Jan Bosch

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Nature Communications16.60

Volume: 11, Issue: 1

Published: May 4, 2020

Abstract

The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and...

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Paper Details

Title

A human monoclonal antibody blocking SARS-CoV-2 infection

DOI

doi.org/10.1038/s41467-020-16256-y

Published Date

May 4, 2020

Journal

Nature Communications

Volume

11

Issue

1

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