ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms
Abstract
Most human protein-coding genes are expressed as multiple isoforms, which greatly expands the functional repertoire of the encoded proteome. While at least one reliable open reading frame (ORF) model has been assigned for every coding gene, the majority of alternative isoforms remains uncharacterized due to (i) vast differences of overall levels between different isoforms expressed from common genes, and (ii) the difficulty of obtaining...
Paper Details
Title
ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms
Published Date
May 11, 2020
Journal
Volume
11
Issue
1
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