Low bone mineral density due to secondary hyperparathyroidism in theGlatmTg(CAG‐A4GALT)mouse model of Fabry disease
Abstract
Low bone mineral density (BMD)—diagnosed as osteoporosis or osteopenia—has been reported as a new characteristic feature of Fabry disease; however, the mechanism underlying the development of low BMD is unknown. We previously revealed that a mouse model of Fabry disease [GlatmTg(CAG-A4GALT)] exhibits impaired functioning of medullary thick ascending limb (mTAL), leading to insufficient Ca2+ reabsorption and hypercalciuria. Here, we investigated...
Paper Details
Title
Low bone mineral density due to secondary hyperparathyroidism in theGlatmTg(CAG‐A4GALT)mouse model of Fabry disease
Published Date
Jun 1, 2020
Journal
Volume
2
Issue
6
Pages
365 - 381
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