Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients
Abstract
Viruses are a constant threat to global health as highlighted by the current COVID-19 pandemic. Currently, lack of data underlying how the human host interacts with viruses, including the SARS-CoV-2 virus, limits effective therapeutic intervention. We introduce Viral-Track, a computational method that globally scans unmapped single-cell RNA sequencing (scRNA-seq) data for the presence of viral RNA, enabling transcriptional cell sorting of...
Paper Details
Title
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients
Published Date
Jun 1, 2020
Journal
Volume
181
Issue
7
Pages
1475 - 1488.e12
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