Co-delivery of superfine nano-silver and solubilized sulfadiazine for enhanced antibacterial functions

For the effective treatment of bacterial infection, it is essential to find a new strategy to deliver antibacterial agents. In the present study, the co-delivery of superfine nano-silver with solubilized sulfadiazine (SD) using cyclodextrin metal-organic frameworks (CD-MOF) as a carrier exhibited superior antibacterial efficacy to insoluble silver sulfadiazine. The abundant hydroxyl moieties in CD-MOF were utilized to reduce Ag precursor into...