P27 Exploring the effect of human rhinovirus-16 infection of expression of pannexin-1 in alveolar cells

Rational and hypothesis: Human rhinovirus (HRV) infections are a major causative agent of upper respiratory tract infection (URTI) and are associated with acute exacerbations of asthma and COPD. URTI is associated with excessive production of mucus within the airway, particularly in sufferers of chronic respiratory conditions. This mucus may lead to altered osmolality within the airway and contribute to hypotonic stimulus of the airway...