Method Development and Validation for Simultaneous Estimation of Glimepiride and Simvastatin by using Reversed Phase High-performance Liquid Chromatography

Volume: 13, Issue: 4, Pages: 1655 - 1659
Published: Apr 30, 2020
Abstract
An analytical method was developed using reverse phase high performance liquid chromatograph (RP-HPLC) system and a C-18 reverse-phase column (Nucleodur C18, 250mm × 4.6mm i.d.,5μ) for simultaneous estimation of simvastatin and glimepiride. Acetonitrile and potassium dihydrogen phosphate buffer pH 4 (75:25, v/v) were used as mobile phase. The flow rate was 1 mL min−1 and the chromatogram of both drugs was detected at wavelength of 232 nm. Method...
Paper Details
Title
Method Development and Validation for Simultaneous Estimation of Glimepiride and Simvastatin by using Reversed Phase High-performance Liquid Chromatography
Published Date
Apr 30, 2020
Volume
13
Issue
4
Pages
1655 - 1659
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