Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy
Abstract
Immune checkpoint blockers (ICBs) have shown great promise at harnessing immune system to combat cancer. However, only a fraction of patients can directly benefit from the anti-programmed cell death protein 1 (aPD1) therapy, and the treatment often leads to immune-related adverse effects. In this context, we developed a prodrug hydrogelator for local delivery of ICBs to boost the host's immune system against tumor. We found that this...
Paper Details
Title
Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy
Published Date
May 1, 2020
Journal
Volume
6
Issue
18
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History