On-cell saturation transfer difference NMR study of Bombesin binding to GRP receptor
Abstract
We report the NMR characterization of the molecular interaction between Gastrin Releasing Peptide Receptor (GRP-R) and its natural ligand bombesin (BN). GRP-R is a transmembrane G-protein coupled receptor promoting the stimulation of cancer cell proliferation; in addition, being overexpressed on the surface of different human cancer cell lines, it is ideal for the development of new strategies for the selective targeted delivery of anticancer...
Paper Details
Title
On-cell saturation transfer difference NMR study of Bombesin binding to GRP receptor
Published Date
Jun 1, 2020
Journal
Volume
99
Pages
103861 - 103861
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