Precision medicine in rare tumors and the need for multicenter trials and international collaboratives: Sinonasal cancer as paradigm

The parapharyngeal space (PPS) can harbor a variety of tumors that can be approached through a wide spectrum of surgical routes. A decisional algorithm on the surgical approach to resect PPS lesions was tested in terms of reliability by retrospectively applying it to a large series of patients.Patients treated at the Unit of Otorhinolaryngology – Head and Neck Surgery of the University of Brescia, Italy, for tumor or tumor-like lesions involving...