What have we learned from animal models of idiosyncratic, drug-induced liver injury?

Volume: 16, Issue: 6, Pages: 475 - 491
Published: May 4, 2020
Abstract
Idiosyncratic, drug-induced liver injury (IDILI) continues to plague patients and restrict the use of drugs that are pharmacologically effective. Mechanisms of IDILI are incompletely understood, and a better understanding would reduce speculation and could help to identify safer drug candidates preclinically. Animal models have the potential to enhance knowledge of mechanisms of IDILI.Numerous hypotheses have emerged to explain IDILI...
Paper Details
Title
What have we learned from animal models of idiosyncratic, drug-induced liver injury?
Published Date
May 4, 2020
Volume
16
Issue
6
Pages
475 - 491
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