Direct enantioseparation of mandelic acid by high‐performance liquid chromatography using a phenyl column precoated with a small amount of cyclodextrin additive in a mobile phase
Abstract
Direct enantioseparation of mandelic acid by high‐performance liquid chromatography (HPLC) with a reversed phase column and a mobile phase containing a small amount of hydroxylpropyl‐β‐cyclodextrin (HP‐β‐CD) was studied as an efficient method for saving consumption of the CD additive. As a result, it was proposed that racemic mandelic acid can be analyzed with a phenyl column by using a mobile phase composed of 10 mM ammonium acetate buffer (pH...
Paper Details
Title
Direct enantioseparation of mandelic acid by high‐performance liquid chromatography using a phenyl column precoated with a small amount of cyclodextrin additive in a mobile phase
Published Date
Apr 28, 2020
Journal
Volume
32
Issue
7
Pages
1020 - 1029
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