Epithelial Repair in the Rabbit Cornea Following Aspects of Epithelial Injury and Repair after Mustard Exposure

Published on Apr 1, 2020in The FASEB Journal4.966
· DOI :10.1096/FASEBJ.2020.34.S1.07007
Marion K. Gordon21
Estimated H-index: 21
(RU: Rutgers University),
Donald R. Gerecke18
Estimated H-index: 18
(RU: Rutgers University)
+ 3 AuthorsYoke-Chen Chang7
Estimated H-index: 7
(RU: Rutgers University)
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#1Sarah E. Seese (MCW: Medical College of Wisconsin)
#2Brett Deml (MCW: Medical College of Wisconsin)H-Index: 4
Last. Elena V. SeminaH-Index: 2
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BACKGROUND The male-abnormal 21 like (MAB21L) genes are important in human ocular development. Homozygous loss of MAB21L1 leads to corneal dystrophy in all affected individuals along with cataracts and buphthalmos in some. The molecular function and downstream pathways of MAB21L factors are largely undefined. RESULTS We generated the first mab21l1 zebrafish mutant carrying a putative loss-of-function allele, c.107delA p.(Lys36Argfs*7). At the final stages of embryonic development, homozygous mab...