Therapeutic peptides targeting the Ras superfamily
Abstract
The Ras superfamily of small GTPases are master regulators of numerous essential processes within the cell, so that when they malfunction, cancer and many other diseases can result. For example, activating Ras mutations are present in approximately 20% of human cancers. As such, they are key therapeutic targets, yet more than three decades of intensive research efforts have failed to produce effective Ras inhibitors in the clinic. This is, in...
Paper Details
Title
Therapeutic peptides targeting the Ras superfamily
Published Date
Apr 13, 2020
Journal
Volume
112
Issue
6
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Notes
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