Tumor heterogeneity in muscle-invasive bladder cancer
Volume: 9, Issue: 6, Pages: 2866 - 2880
Published: Dec 1, 2020
Abstract
Muscle-invasive bladder cancer (MIBC), a highly heterogeneous disease, shows genomic instability and a high mutation rate. Clinical outcomes are variable and responses to conventional chemotherapy differ among patients (due to inter-patient tumor heterogeneity and inter-tumor heterogeneity) and even within each individual tumor (intra-tumor heterogeneity). Emerging evidence indicates that tumor heterogeneity may play an important role in cancer...
Paper Details
Title
Tumor heterogeneity in muscle-invasive bladder cancer
Published Date
Dec 1, 2020
Volume
9
Issue
6
Pages
2866 - 2880
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