Exploring the Biosynthesis of O‐acetylated Sialic Acids using CASD1‐null Mice

Sialic acids (Sias) are a family of nine‐carbon backbone monosaccharides naturally occurring at the outer ends of vertebrate cell surface glycoconjugates. O‐acetyl esters at C4, C7, C8 or C9 of Sias are very common modification of Sias, and can play key roles in a number of biological processes. Cell‐, tissue‐ and individual‐specific variations in Sia O‐acetylation have been reported. Several studies also showed that different cell types...