Assessment of femoral neck bone metabolism using 18F-sodium fluoride PET/CT imaging

Standard of care metabolic bone disease assessment relies on changes to bone quantity, which can only be detected after structural changes occur. To investigate the usefulness of Bone Metabolism Score (BMS), derived from fluorine 18 labeled sodium fluoride (18F-NaF) PET/CT imaging as a biomarker of localized metabolic changes at the femoral neck. In this retrospective study, 139 participants (68 females and 71 males, ages 21–75 years) that had...