Bioactive Non-polar Compounds from Ormocarpum kirkii Bark: a Source of Fungal Multidrug Resistance Inhibitors
Abstract
The bioactivity of the bark ethanol extract of Ormocarpum kirkii S. Moore, Fabaceae, and its fractions obtained by purification with countercurrent chromatography (solvent system hexane-ethanol-water 4:2:2) were screened through the chemosensitization assay of yeast to fluconazole. Two non-polar fractions showed inhibitory activity against resistant Saccharomyces cerevisiae, which overexpresses the major facilitator superfamily transporter in...
Paper Details
Title
Bioactive Non-polar Compounds from Ormocarpum kirkii Bark: a Source of Fungal Multidrug Resistance Inhibitors
Published Date
Apr 1, 2020
Volume
30
Issue
2
Pages
177 - 182
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