Biotechnological Production of Flavonoids: An Update on Plant Metabolic Engineering, Microbial Host Selection, and Genetically Encoded Biosensors

Flavonoids represent a diversified family of phenylpropanoid‐derived plant secondary metabolites. They are widely found in fruits, vegetables, and medicinal herbs. There has been increasing interest on flavonoids because of their proven bioactivity associated with anti‐obesity and anti‐cancer, anti‐inflammatory and anti‐diabetic activity. Low bioavailability of flavonoids is a major challenge restricting their applications. Due to safety and...