Short-Term Efficacy and Tolerability of Paroxetine Versus Placebo for Panic Disorder: A Meta-Analysis of Randomized Controlled Trials

Objective: To explore the short-term efficacy and tolerability of paroxetine in the treatment of panic disorder in adults. Methods: Multiple electronic databases were searched to find randomized controlled trials (RCTs) about paroxetine and panic disorder. The primary efficacy outcomes were the mean change from baseline in total number of full panic attacks and Clinical Global Impression-Severity of Illness (CGI-S) score, the proportion of...