Canagliflozin inhibits vascular smooth muscle cell proliferation and migration: Role of heme oxygenase-1

Volume: 32, Pages: 101527 - 101527
Published: May 1, 2020
Abstract
Recent cardiovascular outcome trials found that sodium-glucose cotransporter-2 (SGLT2) inhibitors reduce cardiovascular disease and mortality in type 2 diabetic patients; however, the underlying mechanisms are not fully known. Since the proliferation and migration of vascular smooth muscle cells (SMCs) contributes to the development of arterial lesions, we hypothesized that SGLT2 inhibitors may exert their beneficial cardiovascular effects by...
Paper Details
Title
Canagliflozin inhibits vascular smooth muscle cell proliferation and migration: Role of heme oxygenase-1
Published Date
May 1, 2020
Volume
32
Pages
101527 - 101527
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