Salidroside ameliorates liver metabonomics in relation to modified gut-liver FXR signaling in furan-induced mice

The study aimed to investigate the ameliorative effect of salidroside (SAL) on the crosstalk among liver metabonomics, gut barrier function and bile acids in furan-induced mice. Forty male mice were randomly divided into the following five groups: CON, FUR 8 (8 mg/kg/day furan), SAL 10 (8 mg/kg/day furan+10 mg/kg/day SAL), SAL 20 (8 mg/kg/day furan+20 mg/kg/day SAL), and SAL 40 (8 mg/kg/day+40 mg/kg/day SAL). Mice were administered with furan...