High-precision image-guided proton irradiation of mouse brain sub-volumes
Abstract
Background and purpose Proton radiotherapy offers the potential to reduce normal tissue toxicity. However, clinical safety margins, range uncertainties, and varying relative biological effectiveness (RBE) may result in a critical dose in tumor-surrounding normal tissue. To assess potential adverse effects in preclinical studies, image-guided proton mouse brain irradiation and analysis of DNA damage repair was established. Material and methods We...
Paper Details
Title
High-precision image-guided proton irradiation of mouse brain sub-volumes
Published Date
May 1, 2020
Journal
Volume
146
Pages
205 - 212
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Notes
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