Distribution of Parkinson’s disease associated RAB39B in mouse brain tissue
Abstract
Pathogenic variants in the gene encoding the small GTPase Ras analogue in Brain 39b (RAB39B) are associated with early-onset parkinsonism. In this study we investigated the expression and localization of RAB39B (RNA and protein) in mouse brain tissue to gain a better understanding of its normal physiological function(s) and role in disease. We developed novel resources, including monoclonal antibodies directed against RAB39B and mice with Rab39b...
Paper Details
Title
Distribution of Parkinson’s disease associated RAB39B in mouse brain tissue
Published Date
Mar 30, 2020
Journal
Volume
13
Issue
1
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