Abstract B51: Novel syngeneic animal model of tobacco-associated oral cancer reveals the activity of in situ anti-CTLA-4
Volume: 8, Issue: 3_Supplement, Pages: B51 - B51
Published: Mar 1, 2020
Abstract
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments. Recently approved anti-PD-1 immune checkpoint inhibitors showed limited activity (≤20%) in HNSCC, highlighting the need to identify new therapeutic options. For this, mouse models that accurately reflect the complexity of the...
Paper Details
Title
Abstract B51: Novel syngeneic animal model of tobacco-associated oral cancer reveals the activity of in situ anti-CTLA-4
Published Date
Mar 1, 2020
Journal
Volume
8
Issue
3_Supplement
Pages
B51 - B51
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