Pancreatic Neuroendocrine Neoplasms: Does Sex Matter?

Pancreatic neuroendocrine neoplasms (PNENs) are rare neoplasms with malignant potential whose incidence is on the rise; their clinical behavior mostly depends on the grade and the stage of the tumor. In addition, recent studies have emphasized a sex difference in PNENs in terms of clinical behavior. Male patients with PNENs have a worse prognosis, a greater risk of disease recurrence after curative surgery, and a higher incidence of...