Interquartile range

Pediatrics

Observational study

Disease

Internal medicine

Pathology

Medicine

Ophthalmology

Parkinson's disease

Cross-sectional study

Confidence interval

Neurology

<h3>Objective</h3> To determine the prevalence and clinical effect of ophthalmologic symptoms in patients with Parkinson disease (PD), compared with controls, using a standardized questionnaire. <h3>Methods</h3> In this observational, cross-sectional, multicenter study, 848 patients with PD and 250 healthy controls completed the Visual Impairment in Parkinson9s Disease Questionnaire (VIPD-Q). The VIPD-Q addressed 4 domains according to structures: (1) ocular surface; (2) intraocular; (3) oculomotor; and (4) optic nerve. The questionnaire also assessed the effect of ophthalmologic symptoms on daily activities. <h3>Results</h3> One or more ophthalmologic symptoms were reported by 82% (95% confidence interval [CI], 80–85) of patients, compared with 48% (95% CI, 42–54) of controls (<i>p</i> &lt; 0.001). Patients with PD experienced more ophthalmologic symptoms across all domains than controls (<i>p</i> &lt; 0.001), as reflected by a higher VIPD-Q total score among patients (median 10 [interquartile range (IQR) 13...

Seeing ophthalmologic problems in Parkinson disease