The influence of nanocarrier architectures on antitumor efficacy of docetaxel nanoparticles
Abstract
To study the structural influence, hybrid amphiphilic copolymer (G2C18) and linear amphiphilic copolymer (PEG45C18) were utilized to prepare docetaxel (DTX)-loaded nanoparticles through an antisolvent precipitation method. The different architectures of the hydrophilic portion affected the particle sizes significantly, and then induced the different antitumor activity. Compared with DTX/PEG45C18 nanoparticles, the antitumor efficacy of DTX/G2C18...
Paper Details
Title
The influence of nanocarrier architectures on antitumor efficacy of docetaxel nanoparticles
Published Date
Jan 1, 2020
Journal
Volume
10
Issue
19
Pages
11074 - 11078
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