Cellular Senescence as a Therapeutic Target for Age-Related Diseases: A Review
Abstract
Life expectancy has increased substantially over the last few decades, leading to a worldwide increase in the prevalence and burden of aging-associated diseases. Recent evidence has proven that cellular senescence contributes substantially to the development of these disorders. Cellular senescence is a state of cell cycle arrest with suppressed apoptosis and concomitant secretion of multiple bioactive factors (the senescence-associated secretory...
Paper Details
Title
Cellular Senescence as a Therapeutic Target for Age-Related Diseases: A Review
Published Date
Mar 17, 2020
Journal
Volume
37
Issue
4
Pages
1407 - 1424
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Notes
History