Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature.

Published on Mar 21, 2020in Journal of Clinical Medicine3.303
· DOI :10.3390/JCM9030866
Claudio De Angelis22
Estimated H-index: 22
(UNITO: University of Turin),
Pablo Cortegoso Valdivia3
Estimated H-index: 3
(UNITO: University of Turin)
+ 5 AuthorsRinaldo Pellicano28
Estimated H-index: 28
(UNITO: University of Turin)
Sources
Abstract
Endoscopic injection of glues, clotting factors, or sclerosing agents is a well-known therapy for the treatment of non-variceal upper gastrointestinal bleeding (NVUGIB), but less is known about endoscopic ultrasound (EUS)-guided treatments. In this setting, literature data are scarce, and no randomized controlled trials are available. We performed a review of the existing literature in order to evaluate the role of EUS-guided therapies in the management of NVUGIB. The most common treated lesions were Dieulafoy’s lesions, pancreatic pseudoaneurysms, and gastrointestinal stromal tumors (GISTs). Mostly, the treatments were performed as a salvage option after failure of conventional endoscopic hemostatic attempts, showing good efficacy and a good safety profile, also documented by Doppler monitoring of treated lesions. EUS-guided therapies may be an effective option in the treatment of refractory NVUGIB, thus avoiding radiological or surgical management. Nevertheless, available literature still lacks robust data.
References40
Newest
#1Timo WeilandH-Index: 4
#2Sabrina RohrerH-Index: 1
Last. Marc O. Schurr (Steinbeis-Hochschule Berlin)H-Index: 18
view all 11 authors...
AbstractSince its market launch in 2007, the endoscopic OTSC clipping system has been the object of intensive clinical research. These data were systematically collected for post-market clinical follow-up (PMCF). The aim of the study was the systematic review of the efficacy and safety of the OTSC System. The PMCF database was systematically searched for clinical data on OTSC therapy of GI hemorrhage (H), acute leaks/perforations (AL) and chronic leaks/fistulae (CL). Major outcomes were successf...
10 CitationsSource
#1Alan N. Barkun (McGill University)H-Index: 84
#2Majid A Almadi (McGill University)H-Index: 22
Last. Marc BardouH-Index: 33
view all 24 authors...
This guideline updates the 2010 International Consensus Recommendations on Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding.
100 CitationsSource
#1Adam J. Kichler (Cleveland Clinic)H-Index: 3
#2Sunguk Jang (Cleveland Clinic)H-Index: 13
: Non-variceal upper gastrointestinal bleeding (NVUGIB) refers to blood loss from the gastrointestinal tract proximal to the ligament of Treitz due to lesions that are non-variceal in origin. The distinction of the bleeding source as non-variceal is important in numerous aspects, but none more so than endoscopic approaches for successful hemostasis. When a patient presents with acute overt blood loss, NVUGIB is a medical emergency, which requires immediate intervention. There have been major str...
8 CitationsSource
#1Malay SharmaH-Index: 15
#2Piyush SomaniH-Index: 6
Last. Rahul TaleleH-Index: 2
view all 5 authors...
4 CitationsSource
#1Livio CipollettaH-Index: 31
#2F. Cipolletta (ISMETT)H-Index: 6
Last. Mario Traina (ISMETT)H-Index: 21
view all 7 authors...
Purpose of review Upper non-variceal gastrointestinal bleeding (UNVGIB) remains an important clinical challenge for endoscopists, requiring skill and expertise for correct management. In this paper, we suggest the best strategy for an effective treatment of this complex category of patients.
6 CitationsSource
#1Idan Levy (CPMC: California Pacific Medical Center)H-Index: 2
#2Kenneth F. Binmoeller (CPMC: California Pacific Medical Center)H-Index: 33
Mediastinal and abdominal vessels have historically served as landmarks to guide routine diagnostic and therapeutic EUS procedures. Major vascular structures including the heart, aorta, celiac axis, portal vein, hepatic veins, mesenteric vessels, and aberrant vascular shunts such as spleno-renal shunts associated with portal hypertension are easily identified. Even smaller vascular structures such as the gastro-duodenal artery, splenic vessels, hepatic artery and portal vein branches can be conf...
3 CitationsSource
#1Joseph J.Y. Sung (CUHK: The Chinese University of Hong Kong)H-Index: 163
#2Philip Cy Chiu (CUHK: The Chinese University of Hong Kong)H-Index: 1
Last. Angel LanasH-Index: 76
view all 18 authors...
Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the ’gold standard9 of management, treatment of these patients can be considered in three stages: pre-endoscopic treatment, endoscopic haemostasis and post-endoscopic management. Since publication of the Asia-Pacific consensus on non-variceal upper gastrointestinal bleeding (NVUGIB) 7 years ago, there have been significant advancements in...
88 CitationsSource
#1Kenneth F. Binmoeller (CPMC: California Pacific Medical Center)H-Index: 33
6 Citations
#1Michael HockeH-Index: 30
#2Barbara Braden (University of Oxford)H-Index: 43
Last. Christoph F. Dietrich (Caritas Hospital)H-Index: 74
view all 4 authors...
A clinical study on 18 cases of sheehan's syndrome, which were available for combined ptiuitary stimulation test consisting of insulin induced hypoglycemia followed by TRH and LHRH stimulation tests, was made. The results are followings; 1) The age at the time of diagnosis of sheehan's disease was ranged from 28 to 55 and averaged 44 years. The mean duration of appearance of clinical sumptoms after episode of postpartum hemorrhage is 11 years. 2) Basal pituitary function was within normal rage i...
13 CitationsSource
#1Kayin Jeffers (Rush University Medical Center)H-Index: 1
#2Shounak Majumder (Mayo Clinic)H-Index: 13
Last. Michael J. Levy (Mayo Clinic)H-Index: 107
view all 4 authors...
5 CitationsSource
Cited By5
Newest
#1Abhishek Bhurwal (RU: Rutgers University)H-Index: 4
#2Anish Patel (RU: Rutgers University)H-Index: 14
Last. Bhaumik Brahmbhatt (Mayo Clinic)H-Index: 6
view all 6 authors...
Objectives: Forrest classification for ulceration has significant intra and inter-observer variability. The endoscopic doppler probe (DOP-US) identifies arterial blood flow at the base to direct th...
Source
#1Christoph F Dietrich (John Radcliffe Hospital)
#2Barbara Braden (John Radcliffe Hospital)H-Index: 43
Last. Christian JenssenH-Index: 18
view all 3 authors...
PURPOSE OF REVIEW To update on recent advances in interventional endoscopic ultrasound (INVEUS) techniques. RECENT FINDINGS The introduction of linear echoendoscopes with larger instrument channels and the combined development of new tools and devices have enabled various new applications of minimally invasive endoscopic ultrasound (EUS)-guided transluminal interventions of the pancreas, biliary system and peri-gastrointestinal structures. In this review, EUS-guided interventions are discussed a...
Source
#1Chaoqun Han (HUST: Huazhong University of Science and Technology)H-Index: 9
#2Xin Ling (HUST: Huazhong University of Science and Technology)
Last. Xiaohua Hou (HUST: Huazhong University of Science and Technology)H-Index: 23
view all 5 authors...
Source
#1Pablo Cortegoso Valdivia (University of Parma)H-Index: 1
#2S. Rizza (UNITO: University of Turin)H-Index: 3
Last. M. Gesualdo (UNITO: University of Turin)H-Index: 1
view all 3 authors...
Source
#1Malay SharmaH-Index: 15
#2Piyush SomaniH-Index: 6
Last. Rahul TaleleH-Index: 2
view all 5 authors...
4 CitationsSource