Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature.

Published on Mar 21, 2020in Journal of Clinical Medicine3.303
· DOI :10.3390/JCM9030866
Claudio De Angelis22
Estimated H-index: 22
(UNITO: University of Turin),
Pablo Cortegoso Valdivia3
Estimated H-index: 3
(UNITO: University of Turin)
+ 5 AuthorsRinaldo Pellicano28
Estimated H-index: 28
(UNITO: University of Turin)
Endoscopic injection of glues, clotting factors, or sclerosing agents is a well-known therapy for the treatment of non-variceal upper gastrointestinal bleeding (NVUGIB), but less is known about endoscopic ultrasound (EUS)-guided treatments. In this setting, literature data are scarce, and no randomized controlled trials are available. We performed a review of the existing literature in order to evaluate the role of EUS-guided therapies in the management of NVUGIB. The most common treated lesions were Dieulafoy’s lesions, pancreatic pseudoaneurysms, and gastrointestinal stromal tumors (GISTs). Mostly, the treatments were performed as a salvage option after failure of conventional endoscopic hemostatic attempts, showing good efficacy and a good safety profile, also documented by Doppler monitoring of treated lesions. EUS-guided therapies may be an effective option in the treatment of refractory NVUGIB, thus avoiding radiological or surgical management. Nevertheless, available literature still lacks robust data.
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This guideline updates the 2010 International Consensus Recommendations on Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding.
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