Advances in Antibody–Drug Conjugate Design: Current Clinical Landscape and Future Innovations
Abstract
The targeted delivery of potent cytotoxic molecules into cancer cells is considered a promising anticancer strategy. The design of clinically effective antibody–drug conjugates (ADCs), in which biologically active drugs are coupled through chemical linkers to monoclonal antibodies, has presented challenges for pharmaceutical researchers. After 30 years of intensive research and development activities, only seven ADCs have been approved for...
Paper Details
Title
Advances in Antibody–Drug Conjugate Design: Current Clinical Landscape and Future Innovations
Published Date
Sep 1, 2020
Journal
Volume
25
Issue
8
Pages
843 - 868
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Notes
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