Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: theWISTERIAtrial protocol

Volume: 10, Issue: 3, Pages: e033009 - e033009
Published: Mar 1, 2020
Abstract
Introduction Patients with head and neck squamous cell carcinoma with locally advanced disease often require multimodality treatment with surgery, radiotherapy and/or chemotherapy. Adjuvant radiotherapy with concurrent chemotherapy is offered to patients with high-risk pathological features postsurgery. While cure rates are improved, overall survival remains suboptimal and treatment has a significant negative impact on quality of life. Cell...
Paper Details
Title
Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: theWISTERIAtrial protocol
Published Date
Mar 1, 2020
Journal
Volume
10
Issue
3
Pages
e033009 - e033009
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