Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter
Abstract
Coumarins have aroused high interests due to their diverse bioactivities. Understanding of its metabolism contributes to determine the druggability of coumarin in vivo.A sensitive and efficient strategy based on ultra-performance liquid chromatography-mass spectrometer (UPLC-MS) analysis combined with various data-processing techniques including metabolomics and multiple mass defect filter (MMDF) was established for the comprehensive screening...
Paper Details
Title
Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter
Published Date
Mar 26, 2020
Journal
Volume
50
Issue
9
Pages
1076 - 1089
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