Temperature- and pH-responsive chitosan-based injectable hydrogels for bone tissue engineering

Spontaneous bone regeneration is heavily restricted because of bone defects, and external mediation is required to enhance repair and regeneration. Bone tissue engineering (BTE) is a multidisciplinary field that offers promising substitutes to traditional methods—namely, autografts, allografts, and xenografts. Amidst the various scaffolds for BTE applications, it has been demonstrated that hydrogels are promising templates for bone regeneration...