Integrated Design of a Mussel‐Inspired Hydrogel Biofilm Composite Structure to Guide Bone Regeneration

Ideal biomedically engineered hydrogels should imitate the physiological environment of natural bone tissue healing. The healing ability of soft tissue is stronger than that of bone tissue, thus leading to premature growth of soft tissue into the bone tissue area of the defect and resulting in poor bone tissue healing at the defect site. In addition, good cellular affinity is necessary to allow for postimplantation fusion with surrounding...